Rita Levi-Montalcini, la dama del sistema nervioso

María Paz Herráez; Marta Lombó

doi:10.18002/ambioc.i19.7340

Autores

María Paz Herráez
Marta Lombó

DOI:

https://doi.org/10.18002/ambioc.i19.7340

Palavras-chave:

Levi-Montalcini Rita, Neurobiología, Sistema nervioso, Científicas

Resumo

El próximo año se cumple una década del fallecimiento de la “dama del sistema nervioso”. Las notables contribuciones de la Dra. Rita Levi-Montalcini a la Ciencia, especialmente en el campo de la Neurobiología, la convierten en una de las científicas clave del siglo XX. Si a ello unimos su trayectoria vital (digna de un guion de Hollywood), su personalidad y su lucha incansable por la justicia social, nos encontraremos ante una de las investigadoras más singulares de la historia.

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Referências

Aloe, L., Alleva, E., Böhm, A. y Levi-Montalcini, R. 1986. Aggressive behavior induces release of nerve growth factor from mouse salivary gland into the bloodstream. Proc. Natl. Acad. Sci., 83:6184–6187.

Aloe, L., Bracci-Laudiero, L., Alleva, E., Lambiase, A., Micera, A. y Tirassa, P. 1994. Emotional stress induced by parachute jumping enhances blood nerve growth factor levels and the distribution of nerve growth factor receptors in lymphocytes. Proc. Natl. Acad. Sci. U. S. A., 91:10440–10444.

Aloe, L., Cozzari, C., Calissano, P. y Levi-Montalcini, R. 1981. Somatic and behavioural postnatal effects of fetal injections of nerve growth factor antibodies in the rat. Nature, 291:413–415.

Aloe, L. y Levi-Montalcini, R. 1977. Mast cells increase in tissues of neonatal rats injected with the nerve growth factor. Brain Res., 133:358–366.

Aloe, L., Rocco, M.L., Bianchi, P. y Manni, L. 2012. Nerve growth factor: from the early discoveries to the potential clinical use. J. Transl. Med., 101(10)1–15.

Cohen, S. 1962. Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. J. Biological Chem., 237:1555-1562.

Cohen, S. y Levi-Montalcini, R. 1956. A nerve growth-stimulating factor isolated from snake venom. Proc. Natl. Acad. Sci. U. S. A., 42:571.

Cohen, S., Levi-Montalcini, R. y Hamburger, V. 1954. A nerve growth-stimulating factor isolated from sarcomas 37 and 180*. Proc. Natl. Acad. Sci. U. S. A., 40:1014-1018.

Hamburger, V. 1934. The effects of wing bud extirpation on the development of the central nervous system in chick embryos. J. Exp. Zool., 68:449–494.

Hogue-Angeletti, R. y Bradshaw, R. 1971. Nerve growth factor from mouse submaxillary gland: amino acid sequence. Proc. Natl. Acad. Sci. U. S. A., 68, 2417–2420.

Leon, A., Buriani, A., Dal Toso, R., Fabris, M., Romanello, S., Aloe, L. y Levi-Montalcini, R., 1994. Mast cells synthesize, store, and release nerve growth factor. Proc. Natl. Acad. Sci. U. S. A., 91:3739–3743.

Levi-Montalcini, R. 1952. Effects of mouse tumor transplantation on the nervous system. N. Y. Acad. Sci., 55:330–344.

Levi-Montalcini, R. 1964. Growth control of nerve cells by a protein factor and its antiserum. Science, 143:105–110.

Levi-Montalcini, R. 1987. The nerve growth factor 35 years later. Science, 237:1154–1162.

Levi-Montalcini, R. 1988. Elogio de la imperfección. Booket Ciencia. ISBN: 9788490660829

Levi-Montalcini, R. 1993. NGF: hacia una nueva frontera en la neurobiología. Alianza Editorial, Madrid. ISBN: 84-206-2763-1

Levi-Montalcini, R. y Aloe, L. 1980. Tropic, trophic, and transforming effects of nerve growth factor. Adv. Biochem. Psychopharmacol., 25:3–15.

Levi-Montalcini, R. y Booker, B. 1960a. Destruction of the sympathetic ganglia in mammals by an antiserum to a nerve-growth protein. Proc. Natl. Acad. Sci., 46:384–391.

Levi-Montalcini, R. y Booker, B. 1960b. Excessive growth of the sympathetic ganglia evoked by a protein isolated from mouse salivary glands. Proc. Natl. Acad. Sci., 46:373–384.

Levi-Montalcini, R. y Levi, G. 1942. Les conséquences de la destruction d’un territoire d’innervation périphérique sur le développement des centres nerveux correspondants dans l’embryon de poulet. Arch. Biol., 53:537–545.

Levi-Montalcini, R. y Levi, G. 1943. Recherches quantitatives sur la marche du processus de différenciation des neurons dans les ganglions spinaux de l’embryon de poule. Arch. Biol., 54:189–206.

Levi-Montalcini, R. y Hamburger, V. 1951. Selective growth stimulating effects of mouse sarcoma on the sensory and sympathetic nervous system of the chick embryo. J. Exp. Zool., 116:321–361.

Levi-Montalcini, R. y Hamburger, V. 1953. A diffusible agent of mouse sarcoma, producing hyperplasia of sympathetic ganglia and hyperneurotization of viscera in the chick embryo. J. Exp. Zool., 123:233–287.

Levi-Montalcini, R., Meyer, H. y Hamburger, V. 1954. In vitro experiments on the effects of mouse sarcomas 180 and 37 on the spinal and sympathetic ganglia of the chick embryo. Cancer Res., 14:49–57.

Levi-Montalcini, R., Skaper, S.D., Dal Toso, R., Petrelli, L. y Leon, A. 1996. Nerve growth factor: from neurotrophin to neurokine. Trends Neurosci., 19:514–520.

Nobel laureate celebrates her centenary. 2009. Nature, 458:1090–1090.

Scott, J., Selby, M., Urdea, M., Quiroga, M., Bell, G.I. y Rutter, W.J. 1983. Isolation and nucleotide sequence of a cADN encoding the precursor of mouse nerve growth factor. Nature, 302:538–540.

Strata, P. 2018. Rita Levi-Montalcini and her major contribution to neurobiology. Rend. Lincei, 29:737–753.

Wise, B.L., Seidel, M.F. y Lane, N.E. 2020. The evolution of nerve growth factor inhibition in clinical medicine. Nat. Rev. Rheumatol., 171(17):34–46.